Subject(s)
Goldenhar Syndrome/complications , Humans , Infant , Male , Tetralogy of Fallot/complicationsSubject(s)
Heart Neoplasms/pathology , Humans , Infant , Male , Myocardium/pathology , Rhabdomyoma/pathologyABSTRACT
Fourteen infants ranging in age from 18 days to 10 months (median age = 4 months) underwent surgical repair of total anomalous pulmonary venous connection (TAPVC) between September, 1988 and December, 1989. The anomalous drainage was supracardiac in nine, cardiac in two, infracardiac in one and mixed in one. One patient had a complex type of TAPVC. There were two hospital deaths, one a critically ill three week old infant with obstructed infracardiac TAPVC and the other with complex TAPVC. There was no late death. All twelve survivors are in NYHA functional Class 1. Postoperative echocardiography revealed unobstructed pulmonary blood flow in all of them. Surgical correction of TAPVC in infancy has been performed with gratifying results. A high index of suspicion, early diagnosis, prompt referral and an aggressive surgical approach are essential for success in this otherwise lethal condition.
Subject(s)
Cardiac Surgical Procedures/methods , Follow-Up Studies , Heart Defects, Congenital/pathology , Humans , Infant , Infant, Newborn , Pulmonary Veins/abnormalitiesSubject(s)
Adolescent , Adult , Aged , Arrhythmias, Cardiac/therapy , Child , Equipment Contamination , Equipment Failure , Female , Humans , Male , Middle Aged , Pacemaker, Artificial/adverse effects , RiskSubject(s)
Adult , Aged , Coronary Artery Bypass , Coronary Disease/surgery , Female , Humans , Male , Middle AgedABSTRACT
Estradiol-induced incorporation of radioactive uridine and leucine into the uterus of rat was inhibited by simultaneous treatment with an analogue of gonadotropin releasing hormone. The inhibitory action of gonadotropin releasing hormone was not mediated through modulation of estradiol receptor content. However, estradiol-induced increase in the level of poly(A) polymerase was inhibited by gonadotropin releasing hormone analogue, indicating that the inhibitory effect might involve post-transcriptional phenomenon.